Overview on Pediatric Myelodysplastic Syndrome: A Review

Myelodysplastic syndrome (MDS) is a set of clonal bone marrow diseases in children that are characterised by peripheral cytopenia, dysplastic alterations the marrow, and inefficient hematopoiesis. MDS uncommon children, with just 1-4 occurrences per million afflicted. Adults, particularly elderly, more susceptible to disease. Some hereditary disorders, such as Fanconi's anaemia, Shwachman's, Down's syndromes, known predispose developing MDS. JCML monosomy 7 two most frequent paediatric types, both which affect their early years. Approximately 20% juvenile myelodysplastic cases discovered chance during normal laboratory testing or course suspected failure (IBMF). Differentiating low blast numbers from aplastic anaemia (AA) excess blasts AML key diagnostic issues this condition. Bone transplantation stem cell treatment choice cases. In article we discuss disease epidemiology, diagnosis, treatment.